Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PAB2248bioY biotin biosynthesis protein. (163 aa)    
Predicted Functional Partners:
PAB2261
Cobalt transport protein, cbiQ family.
 
 0.992
PAB2260
ABC transporter, ATP-binding protein, substrate unknown; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.984
PAB0249
ABC ABC-type transport system, ATPase component, substrate unknown; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.953
birA-like
birA-like biotin operon repressor/biotin--[acetyl coA carboxylase] ligase homolog.
 
   
 0.921
birA
Biotin-(acetyl-coA carboxylase) ligase.
 
   
 0.591
tgtA
Queuine-archaeosine tRNA ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
 
     0.433
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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