Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAB2298Transcriptional regulator, arsR family. (134 aa)    
Predicted Functional Partners:
PAB3022
Hypothetical protein.
     
 0.954
PAB1045
Hypothetical protein.
       0.717
PAB0828
Polysaccharide deacetylase, putative.
 
     0.632
PAB0160
Integral membrane protein, function unknown.
       0.614
PAB2299
Transcriptional regulator protein Lrp-Asn family.
  
  
 0.611
thiL
thiL thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.608
PAB0825
Translation initiation inhibitor; Belongs to the RutC family.
       0.604
PAB0826
Integral membrane protein.
       0.566
PAB0036
Hypothetical protein.
       0.565
cS
Zinc-transporting ATPase (translocating P-type) (EC 3.6.3.5).
 
  
 0.545
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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