Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PAB2437Hypothetical protein, DUF114 family. (280 aa)    
Predicted Functional Partners:
PAB2181
Hypothetical protein.
       0.776
PAB2180
Hypothetical protein, containing ATP/GTP-binding site motif A; Belongs to the UPF0273 family.
       0.734
cpa
Cpa carbamate kinase-like carbamoylphosphate synthetase.
       0.716
PAB1994
Hypothetical protein.
       0.639
PAB0081
Hypothetical protein, containing archaeal coiled-coil domain.
       0.607
PAB0082
Queuine tRNA-ribosyltransferase.
       0.606
tbp
TATA box binding protein TFIIB-BBRE complex, chain A; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation (By similarity).
       0.583
PAB0178
Conserved archaebacterial protein.
       0.498
PAB0743
Hypothetical protein; Belongs to the UPF0127 family.
 
     0.458
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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