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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PABs6089Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain. (62 aa)    
Predicted Functional Partners:
ftsZ-2
ftsZ-2 cell division GTPase, ftsZ homolog; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.768
PAB0853
Hypothetical protein.
       0.729
soj
ATPase involved in chromosome partitioning, minD/MRP superfamily.
     
 0.614
cgi121
Hypothetical protein; Component of the KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. Cgi121 is not required for tRNA modification.
       0.592
cobB
NAD-dependent protein deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. Belongs to the sirtuin family. Class III subfamily.
   
    0.517
PAB1318
nadM nicotinamide nucleotide adenylyltransferase.
   
    0.478
aspB-2
aspC-2 aspartate aminotransferase (EC 2.6.1.1).
     
 0.475
PAB1524
Permease of the major facilitator family, putative.
       0.460
PAB0854
acdA-3 acetate--coA ligase (ADP-forming) (EC 6.2.1.13), alpha chain.
       0.403
iorA-1
iorA indolepyruvate ferredoxin oxidoreductase, subunit alpha; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.403
Your Current Organism:
Pyrococcus abyssi
NCBI taxonomy Id: 272844
Other names: P. abyssi GE5, Pyrococcus abyssi GE5, Pyrococcus abyssi str. GE5, Pyrococcus abyssi str. Orsay, Pyrococcus abyssi strain GE5
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