STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCAS0B00430Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck. (488 aa)    
Predicted Functional Partners:
NCAS0B08080
Uncharacterized protein.
   
 0.997
NCAS0A08860
Uncharacterized protein.
    
 
 0.977
NCAS0I02490
WD_REPEATS_REGION domain-containing protein.
   
 0.906
NCAS0A03250
PNPLA domain-containing protein.
     
  0.900
NCAS0F00340
Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.
     
  0.900
NCAS0G00340
PNPLA domain-containing protein.
     
  0.900
NCAS0G02370
Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
NCAS0F02150
Uncharacterized protein.
    
 0.898
NCAS0F01110
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.861
NCAS0A03450
Uncharacterized protein.
    
 0.824
Your Current Organism:
Naumovozyma castellii
NCBI taxonomy Id: 1064592
Other names: N. castellii CBS 4309, Naumovozyma castellii CBS 4309
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