STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crtIPhytoene dehydrogenase; Converts phytoene into all-trans-neurosporene as the major product, via the intermediary of phytofluene and zeta-carotene, by the introduction of three double bonds. Both intermediates, phytofluene and zeta-carotene, can be used as substrates and converted to neurosporene. 1,2-epoxy phytoene is also a suitable substrate whereas the C30 diapophytoene is not; Belongs to the carotenoid/retinoid oxidoreductase family. (524 aa)    
Predicted Functional Partners:
crtB
Phytoene synthase; Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity). Belongs to the phytoene/squalene synthase family.
 
 0.999
crtC
Hydroxyneurosporene synthase; Involved in the biosynthesis of carotenoids spheroidene and spirilloxanthin. Catalyzes the hydration of neurosporene to the corresponding hydroxylated carotenoids 1-HO-neurosporene and that of lycopene to 1-HO-lycopene. It exhibits negligible activity in converting HO-neurosporene, HO-lycopene, or any other derivative such as spheroidene, 1-HO-3,4-didehydrolycopene.
 
 
 0.993
ADE85502.1
Phytoene synthase family protein.
  
 
 0.964
crtA
Spheroidene monooxygenase; Catalyzes the asymmetrical introduction of one keto group at the C-2 position of spheroidene and two keto groups at the C-2 and C-2' positions of spirilloxanthin.
 
  
 0.961
tspO
Signal transduction protein TspO; Belongs to the TspO/BZRP family.
 
  
 0.927
bchI
Magnesium chelatase ATPase subunit I; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX; Belongs to the Mg-chelatase subunits D/I family.
 
  
 0.917
crtE
Farnesyltranstransferase; Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes. Belongs to the FPP/GGPP synthase family.
 
  
 0.914
bchC
2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; This protein catalyzes the penultimate step in bacteriochlorophyll a biosynthesis.
 
  
 0.888
bchD
Magnesium chelatase ATPase subunit D; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX; Belongs to the Mg-chelatase subunits D/I family.
 
  
 0.885
bchP
Geranylgeranyl reductase; Catalyzes the stepwise hydrogenation of geranylgeraniol to phytol during bacteriochlorophyll A (BchlA) biosynthesis.
 
  
 0.874
Your Current Organism:
Rhodobacter capsulatus
NCBI taxonomy Id: 272942
Other names: R. capsulatus SB 1003, Rhodobacter capsulatus SB 1003
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.