STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobA1uroporphyrinogen-III C-methyltransferase-1; Belongs to the precorrin methyltransferase family. (263 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 0.985
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.979
sat
Bifunctional sulfate adenylyltransferase/adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.979
cysI
Sulfite reductase (NADPH) hemoprotein, beta subunit.
 
  
 0.973
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.925
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.920
cobI
Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.914
cobA2
uroporphyrinogen-III C-methyltransferase-2; Belongs to the precorrin methyltransferase family.
  
  
 
0.913
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.858
ADE85340.1
Conserved hypothetical protein.
  
  
 0.849
Your Current Organism:
Rhodobacter capsulatus
NCBI taxonomy Id: 272942
Other names: R. capsulatus SB 1003, Rhodobacter capsulatus SB 1003
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.