node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADE84627.1 | amt | RCAP_rcc00862 | RCAP_rcc01792 | Divalent anion:Na+ symporter. | Ammonium transporter. | 0.721 |
amt | ADE84627.1 | RCAP_rcc01792 | RCAP_rcc00862 | Ammonium transporter. | Divalent anion:Na+ symporter. | 0.721 |
amt | draG | RCAP_rcc01792 | RCAP_rcc03017 | Ammonium transporter. | ADP-ribosyl-[dinitrogen reductase] hydrolase. | 0.627 |
amt | glnB1 | RCAP_rcc01792 | RCAP_rcc01673 | Ammonium transporter. | Nitrogen regulatory protein P-II-1; Belongs to the P(II) protein family. | 0.948 |
amt | glnB2 | RCAP_rcc01792 | RCAP_rcc03387 | Ammonium transporter. | Nitrogen regulatory protein P-II-2; Belongs to the P(II) protein family. | 0.967 |
amt | glnD | RCAP_rcc01792 | RCAP_rcc00466 | Ammonium transporter. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.777 |
amt | glnE | RCAP_rcc01792 | RCAP_rcc02414 | Ammonium transporter. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.769 |
amt | gltB | RCAP_rcc01792 | RCAP_rcc00161 | Ammonium transporter. | Glutamate synthase (NADPH), alpha subunit. | 0.781 |
amt | ispDF | RCAP_rcc01792 | RCAP_rcc01795 | Ammonium transporter. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.573 |
amt | ntrB | RCAP_rcc01792 | RCAP_rcc01797 | Ammonium transporter. | Nitrogen regulation protein NtrB; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC. In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC. | 0.835 |
amt | ntrC | RCAP_rcc01792 | RCAP_rcc01798 | Ammonium transporter. | Nitrogen assimilation regulatory protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.731 |
draG | amt | RCAP_rcc03017 | RCAP_rcc01792 | ADP-ribosyl-[dinitrogen reductase] hydrolase. | Ammonium transporter. | 0.627 |
draG | glnB1 | RCAP_rcc03017 | RCAP_rcc01673 | ADP-ribosyl-[dinitrogen reductase] hydrolase. | Nitrogen regulatory protein P-II-1; Belongs to the P(II) protein family. | 0.634 |
draG | glnB2 | RCAP_rcc03017 | RCAP_rcc03387 | ADP-ribosyl-[dinitrogen reductase] hydrolase. | Nitrogen regulatory protein P-II-2; Belongs to the P(II) protein family. | 0.634 |
draG | glnD | RCAP_rcc03017 | RCAP_rcc00466 | ADP-ribosyl-[dinitrogen reductase] hydrolase. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.613 |
draG | ntrC | RCAP_rcc03017 | RCAP_rcc01798 | ADP-ribosyl-[dinitrogen reductase] hydrolase. | Nitrogen assimilation regulatory protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.424 |
glnB1 | amt | RCAP_rcc01673 | RCAP_rcc01792 | Nitrogen regulatory protein P-II-1; Belongs to the P(II) protein family. | Ammonium transporter. | 0.948 |
glnB1 | draG | RCAP_rcc01673 | RCAP_rcc03017 | Nitrogen regulatory protein P-II-1; Belongs to the P(II) protein family. | ADP-ribosyl-[dinitrogen reductase] hydrolase. | 0.634 |
glnB1 | glnB2 | RCAP_rcc01673 | RCAP_rcc03387 | Nitrogen regulatory protein P-II-1; Belongs to the P(II) protein family. | Nitrogen regulatory protein P-II-2; Belongs to the P(II) protein family. | 0.905 |
glnB1 | glnD | RCAP_rcc01673 | RCAP_rcc00466 | Nitrogen regulatory protein P-II-1; Belongs to the P(II) protein family. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.979 |