STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_0099TRAP-T family sorbitol/mannitol transporter, DctQ (4TMs) subunit; IMG reference gene:2512955090; PFAM: Tripartite ATP-independent periplasmic transporters, DctQ component. (204 aa)    
Predicted Functional Partners:
RSP_6094
TRAP-T family sorbitol/mannitol transporter, DctM (12TMs) subunit; IMG reference gene:2512955089; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit.
  
 0.965
smoM
TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, SmoM; Part of the tripartite ATP-independent periplasmic (TRAP) transport system TakPQM involved in the uptake of alpha-keto acids. This protein specifically binds alpha-keto acids including pyruvate, oxobutyrate, oxovalerate and 4-methyl-2-oxovalerate. Ligand-binding affinity increases with the increasing chain length of the aliphatic backbone of the ligand. Is not able to bind alpha-ketoglutarate. Belongs to the bacterial solute-binding protein 7 family.
 
    0.824
RSP_3370
TRAP-T family transporter, DctM (12 TMs) subunit; IMG reference gene:2512956881; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit.
  
 0.811
RSP_3372
TRAP-T family transporter, periplasmic binding protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
 
    0.796
RSP_2321
Putative TRAP-T family transporter, DctM (12TMs) subunit; IMG reference gene:2512954255; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, DctM subunit.
  
 0.559
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
   
    0.457
RSP_1419
TRAP-T family transporter, small (4 TMs) inner membrane subunit; IMG reference gene:2512957354; PFAM: Tripartite tricarboxylate transporter TctB family.
  
    0.422
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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