STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ucpA1Short-chain dehydrogenase; IMG reference gene:2512955172; PFAM: short chain dehydrogenase. (246 aa)    
Predicted Functional Partners:
RSP_0173
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase; IMG reference gene:2512955171; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
 
 0.880
nuoCD
NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.815
sucD
Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
 
 0.569
RSP_0594
Putative choline sulfatase; IMG reference gene:2512955609; PFAM: Choline sulfatase enzyme C terminal; Sulfatase; TIGRFAM: choline-sulfatase.
   
 
 0.547
RSP_3216
Putative DNA repair exonuclease; IMG reference gene:2512956728.
   
 
 0.534
RSP_0175
Lactate dehydrogenase-related dehydrogenase; IMG reference gene:2512955173; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
 
   0.532
gabD4
Succinate semialdehyde dehydrogenase; IMG reference gene:2512956050; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase; truncated by 19 aa; Belongs to the aldehyde dehydrogenase family.
 
 
   0.527
pfkB
6-phosphofructokinase; IMG reference gene:2512954269; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family.
   
    0.521
RSP_0172
Putative transcriptional regulators; IMG reference gene:2512955170; PFAM: Helix-turn-helix; Predicted transcriptional regulator (DUF2083).
  
    0.489
RSP_1505
Putative Metallo-phosphoesterase; IMG reference gene:2512953398; TIGRFAM: phosphoesterase, MJ0936 family.
   
   0.484
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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