STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
bchEAnaerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase; Involved in the tetrapyrrole biosynthetic pathways leading to chlorophyll and bacteriochlorophyll (BChl). Catalyzes the anaerobic formation of the isocyclic ring (E-ring) in Mg-protoporphyrin monomethyl ester (MPE) to yield protochlorophyllide a (PChlide a) via a six-electron oxidation and the formation of an oxo group at position C13 using oxygen from a water molecule. (612 aa)    
Predicted Functional Partners:
bchJ
Bacteriochlorophyll synthase, 23 kDa subunit (bchJ); IMG reference gene:2512955287; PFAM: V4R domain; TIGRFAM: bacteriochlorophyll 4-vinyl reductase.
 
 
 0.999
bchM
Mg-protoporphyrin IX methyltransferase; IMG reference gene:2512955296; PFAM: Methyltransferase small domain; Magnesium-protoporphyrin IX methyltransferase C-terminus; TIGRFAM: magnesium protoporphyrin O-methyltransferase.
 
 
 0.988
acsF
Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family.
  
 
 0.977
bchF
IMG reference gene:2512955291; PFAM: 2-vinyl bacteriochlorophyllide hydratase (BCHF); TIGRFAM: 2-vinyl bacteriochlorophyllide hydratase.
 
  
 0.970
bchG
Chlorophyll synthase; Catalyzes the esterification of bacteriochlorophyllide a by geranylgeraniol-PPi.
 
  
 0.965
bchP
Geranylgeranyl hydrogenase; IMG reference gene:2512955284; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family.
 
  
 0.956
bchN
Ferredoxin protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
 
 
 0.945
bchB
Ferredoxin protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
 
 
 0.944
bchH
Cobaltochelatase CobN subunit; Involved in bacteriochlorophyll pigment biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg- protoroporphyrin IX.
 
  
 0.935
bchC
Chlorophyll synthesis pathway, bchC; This protein catalyzes the penultimate step in bacteriochlorophyll a biosynthesis.
  
  
 0.902
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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