STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (182 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.999
ureG
Urease accessory protein G; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.998
ureB
Urease, beta subunit; IMG reference gene:2512955317; PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; Belongs to the urease beta subunit family.
 
  
 0.974
ureA
Urease, gamma subunit; IMG reference gene:2512955318; PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; Belongs to the urease gamma subunit family.
 
  
 0.971
ureC
IMG reference gene:2512955314; PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.971
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.948
hypB
Hydrogenase nickel incorporation protein HypB; IMG reference gene:2512955517; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
  
 
 0.940
RSP_0301
Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512955309; TIGRFAM: urea ABC transporter, urea binding protein.
 
   
 0.794
RSP_0298
IMG reference gene:2512955306; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; TIGRFAM: urea ABC transporter, ATP-binding protein UrtD.
 
   
 0.769
RSP_0299
Amino acid/amide ABC transporter membrane protein 2, HAAT family; IMG reference gene:2512955307; PFAM: Branched-chain amino acid transport system / permease component; TIGRFAM: urea ABC transporter, permease protein UrtC; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.745
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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