STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_0357Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. (393 aa)    
Predicted Functional Partners:
RSP_0356
Protease FtsH subunit HflC; HflC and HflK could regulate a protease.
 
 0.999
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.986
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.898
RSP_0355
Putative serine protease; IMG reference gene:2512955365; PFAM: Trypsin; TIGRFAM: periplasmic serine protease, Do/DeqQ family; extended by 52 aa; Belongs to the peptidase S1C family.
 
 
 0.852
gor
NADPH-glutathione reductase; Maintains high levels of reduced glutathione.
  
 
 0.767
RSP_1521
Hypothetical protein; IMG reference gene:2512953416.
   
  
 0.749
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; IMG reference gene:2512956789; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Belongs to the TPP enzyme family.
      
 0.747
RSP_6076
Hypothetical protein; IMG reference gene:2512954827.
      
 0.747
cbbI
Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.733
yidC
Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.715
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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