STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (262 aa)    
Predicted Functional Partners:
RSP_2679
IMG reference gene:2512954624; PFAM: Eukaryotic and archaeal DNA primase small subunit; ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain; DNA ligase D; DNA polymerase LigD, polymerase domain; DNA ligase D, 3'-phosphoesterase domain.
 
  
 0.949
ku-2
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
  
 
 
0.915
RSP_0521
Putative Zn-containing dehydrogenase; IMG reference gene:2512955533; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
  
    0.777
RSP_0522
Putative oxidoreductase; IMG reference gene:2512955534; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
    0.776
lig2
DNA ligase; IMG reference gene:2512954357; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase, ATP-dependent, PP_1105 family.
 
  
 0.600
RSP_0939
Hypothetical protein; IMG reference gene:2512955974; PFAM: Protein of unknown function DUF72.
 
    0.587
RSP_0946
IMG reference gene:2512955981; PFAM: Eukaryotic DNA topoisomerase I, catalytic core.
 
    0.569
RSP_0518
Putative glycosyltransferase protein; IMG reference gene:2512955530; PFAM: Glycosyl transferases group 1.
 
    0.568
RSP_0520
NAD-dependent dehydratase/epimerase; IMG reference gene:2512955532; PFAM: NAD dependent epimerase/dehydratase family.
 
    0.546
RSP_0517
Hypothetical protein; IMG reference gene:2512955529.
  
    0.482
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.