STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nifVHomocitrate synthase; IMG reference gene:2512955541; PFAM: HMGL-like; TIGRFAM: homocitrate synthase NifV; extended by 33 aa on 3' end due to sequence change; Belongs to the alpha-IPM synthase/homocitrate synthase family. (391 aa)    
Predicted Functional Partners:
nifW
Nitrogenase stabilizing/protective protein; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family.
 
  
 0.986
nifB
NifB family--FeMo cofactor biosynthesis protein; IMG reference gene:2512955559; PFAM: Radical SAM superfamily; Dinitrogenase iron-molybdenum cofactor; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB.
 
  
 0.969
leuC
Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 0.966
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.963
nifQ
Putative nitrogen fixation protein nifQ; IMG reference gene:2512955545; PFAM: NifQ.
 
  
 0.954
nifN
Nitrogenase molybdenum-iron protein beta chain, nifN; IMG reference gene:2512955549; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron cofactor biosynthesis protein NifN; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.949
nifE
nifE, nitrogenase molybdenum-cofactor synthesis protein; IMG reference gene:2512955550; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.943
RSP_2723
2-isopropylmalate synthase; IMG reference gene:2512954668; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; extended by 9 aa; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
0.942
RSP_1255
Phosphate acetyltransferase; IMG reference gene:2512956299; PFAM: MaoC like domain; Phosphate acetyl/butaryl transferase.
  
 
 0.938
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
  
0.935
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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