STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_0576Na+/solute symporter; IMG reference gene:2512955591; PFAM: Sodium:solute symporter family; TIGRFAM: probable sodium:solute symporter, VC_2705 subfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (605 aa)    
Predicted Functional Partners:
RSP_0577
IMG reference gene:2512955592; TIGRFAM: putative solute:sodium symporter small subunit; extended by 7 aa.
 
    0.983
RSP_0575
Putative signal transduction protein containing cyclic nucleotide-binding and CBS domains; IMG reference gene:2512955590; PFAM: Putative nucleotidyltransferase substrate binding domain; CBS domain; Cyclic nucleotide-binding domain; Putative nucleotidyltransferase DUF294.
 
  
 0.976
RSP_0574
Hypothetical protein; IMG reference gene:2512955589.
 
    0.917
RSP_3141
Putative membrane protein; IMG reference gene:2512956650; PFAM: Protein of unknown function, DUF485.
  
  
 0.908
RSP_0572
Putative exonuclease; IMG reference gene:2512955587; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
 
    0.858
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.823
adk-2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
    0.671
acsA
propionyl-CoA synthetase; IMG reference gene:2512953489; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; truncated by 8 aa.
  
  
 0.621
phoB
IMG reference gene:2512955588; PFAM: Response regulator receiver domain.
  
    0.597
gltA
Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
  
 0.446
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.