STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_0629Hypothetical protein; IMG reference gene:2512955645; TIGRFAM: conserved hypothetical protein, steroid delta-isomerase-related. (133 aa)    
Predicted Functional Partners:
RSP_0628
IMG reference gene:2512955644; PFAM: Acetyltransferase (GNAT) family.
 
    0.966
RSP_0627
Putative amidohydrolase; IMG reference gene:2512955643; PFAM: Carbon-nitrogen hydrolase.
 
    0.953
RSP_0630
Protein-tyrosine-phosphatase; IMG reference gene:2512955646; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
 
    0.945
RSP_0631
Hypothetical protein; IMG reference gene:2512955647; PFAM: Uncharacterised protein family (UPF0262); Belongs to the UPF0262 family.
  
    0.845
hisD1
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.808
lctB
Lactate dehydrogenase; IMG reference gene:2512955858; PFAM: FMN-dependent dehydrogenase.
 
 
    0.647
RSP_3665
Transcriptional regulator, LuxR family; IMG reference gene:2512957201; PFAM: Bacterial regulatory proteins, luxR family; Autoinducer binding domain.
   
    0.645
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
   
    0.614
infA
Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
       0.547
RSP_0625
Putative Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
    0.542
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.