node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_1232 | RSP_3100 | RSP_1232 | RSP_3100 | Putative integral membrane protein; Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll. Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone. Belongs to the HemJ family. | Putative membrane protein; IMG reference gene:2512956602; PFAM: Uncharacterised protein family (UPF0093). | 0.900 |
RSP_1232 | hemE | RSP_1232 | RSP_0680 | Putative integral membrane protein; Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll. Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone. Belongs to the HemJ family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.723 |
RSP_1232 | hemF | RSP_1232 | RSP_0682 | Putative integral membrane protein; Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll. Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone. Belongs to the HemJ family. | Coproporphyrinogen oxidase; IMG reference gene:2512955703; PFAM: Coproporphyrinogen III oxidase. | 0.978 |
RSP_1232 | hemN | RSP_1232 | RSP_0317 | Putative integral membrane protein; Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll. Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone. Belongs to the HemJ family. | Coproporphyrinogen III oxidase; Anaerobic transformation of coproporphyrinogen III into protoporphyrinogen IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.967 |
RSP_1232 | hemZ | RSP_1232 | RSP_0699 | Putative integral membrane protein; Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll. Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone. Belongs to the HemJ family. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.940 |
RSP_3100 | RSP_1232 | RSP_3100 | RSP_1232 | Putative membrane protein; IMG reference gene:2512956602; PFAM: Uncharacterised protein family (UPF0093). | Putative integral membrane protein; Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX. Is involved in the biosynthesis of tetrapyrrole molecules like heme and chlorophyll. Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone. Belongs to the HemJ family. | 0.900 |
RSP_3100 | hemE | RSP_3100 | RSP_0680 | Putative membrane protein; IMG reference gene:2512956602; PFAM: Uncharacterised protein family (UPF0093). | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.654 |
RSP_3100 | hemF | RSP_3100 | RSP_0682 | Putative membrane protein; IMG reference gene:2512956602; PFAM: Uncharacterised protein family (UPF0093). | Coproporphyrinogen oxidase; IMG reference gene:2512955703; PFAM: Coproporphyrinogen III oxidase. | 0.976 |
RSP_3100 | hemN | RSP_3100 | RSP_0317 | Putative membrane protein; IMG reference gene:2512956602; PFAM: Uncharacterised protein family (UPF0093). | Coproporphyrinogen III oxidase; Anaerobic transformation of coproporphyrinogen III into protoporphyrinogen IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.965 |
RSP_3100 | hemZ | RSP_3100 | RSP_0699 | Putative membrane protein; IMG reference gene:2512956602; PFAM: Uncharacterised protein family (UPF0093). | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.943 |
ccoN | ccoO | RSP_0696 | RSP_0695 | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | IMG reference gene:2512955716; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II. | 0.999 |
ccoN | ccoP | RSP_0696 | RSP_0693 | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | Cbb3-type cytochrome c oxidase CcoP subunit; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit. From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place. The complex also functions as a proton pump; Belongs to the CcoP / FixP family. | 0.999 |
ccoN | fnrL | RSP_0696 | RSP_0698 | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | Crp-Fnr regulatory protein (FnrL); Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes. | 0.757 |
ccoN | hemN | RSP_0696 | RSP_0317 | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | Coproporphyrinogen III oxidase; Anaerobic transformation of coproporphyrinogen III into protoporphyrinogen IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.838 |
ccoN | hemZ | RSP_0696 | RSP_0699 | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.827 |
ccoN | ompW | RSP_0696 | RSP_2507 | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | Outer membrane protein; IMG reference gene:2512954452; PFAM: OmpW family. | 0.902 |
ccoO | ccoN | RSP_0695 | RSP_0696 | IMG reference gene:2512955716; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II. | Cbb3-type cytochrome oxidase CcoN subunit; IMG reference gene:2512955717; PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. | 0.999 |
ccoO | ccoP | RSP_0695 | RSP_0693 | IMG reference gene:2512955716; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II. | Cbb3-type cytochrome c oxidase CcoP subunit; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit. From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place. The complex also functions as a proton pump; Belongs to the CcoP / FixP family. | 0.999 |
ccoO | hemN | RSP_0695 | RSP_0317 | IMG reference gene:2512955716; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II. | Coproporphyrinogen III oxidase; Anaerobic transformation of coproporphyrinogen III into protoporphyrinogen IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.815 |
ccoO | hemZ | RSP_0695 | RSP_0699 | IMG reference gene:2512955716; PFAM: Cytochrome C oxidase, mono-heme subunit/FixO; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.804 |