STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_0788Putative kinase involved in propanediol utilization; IMG reference gene:2512955815. (277 aa)    
Predicted Functional Partners:
cobE
Putative precorrin methylase; IMG reference gene:2512954787; PFAM: Cobalamin synthesis G C-terminus.
 
  
 0.956
cobC
L-threonine O-3-phosphate decarboxylase; IMG reference gene:2512955816; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase.
 
  
 0.949
cobT
Cobaltochelatase CobT subunit; IMG reference gene:2512953890; PFAM: Cobalamin biosynthesis protein CobT VWA domain; Cobalamin biosynthesis protein CobT; TIGRFAM: cobaltochelatase, CobT subunit.
   
  
 0.835
cobS
Cobaltochelatase CobS subunit; IMG reference gene:2512953893; PFAM: AAA domain (dynein-related subfamily); Cobaltochelatase CobS subunit N terminal; TIGRFAM: cobaltochelatase, CobS subunit; truncated by 20 aa.
   
  
 0.833
cobN
Cobaltochelatase CobN subunit; IMG reference gene:2512954781; PFAM: CobN/Magnesium Chelatase.
 
  
 0.830
RSP_3218
5,6-dimethylbenzimidazole synthase; IMG reference gene:2512956729; PFAM: Nitroreductase family; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase.
  
  
 0.825
RSP_0787
Hypothetical protein; IMG reference gene:2512955814.
  
    0.794
MeaA
(R)-ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R.sphaeroides growth on acetate as sole carbon source. Is highly specific for its substrate, ethylmalonyl-CoA, and accepts methylmalonyl-CoA only at 0.2% relative activity.
   
  
 0.695
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.669
cobJ
Precorrin-3 methyltransferase; IMG reference gene:2512954784; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase.
 
  
 0.668
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.