Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RSP_0899Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (162 aa)    
Predicted Functional Partners:
RSP_0769
IMG reference gene:2512955798; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily.
  
 
  0.938
RSP_2389
IMG reference gene:2512954334; PFAM: Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.936
gor
NADPH-glutathione reductase; Maintains high levels of reduced glutathione.
 
 
 0.929
RSP_0897
IMG reference gene:2512955929; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain.
  
 
  0.919
gshB
Glutathione synthase; IMG reference gene:2512953722; PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; Belongs to the prokaryotic GSH synthase family.
     
 0.910
Gst
IMG reference gene:2512956187; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; truncated by 20 aa.
   
 
  0.901
RSP_3110
IMG reference gene:2512956615; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain.
   
 
  0.901
RSP_3111
IMG reference gene:2512956616; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily.
   
 
  0.901
RSP_3377
Glutathione S-transferase family protein; IMG reference gene:2512956888.
   
 
  0.901
RSP_1499
IMG reference gene:2512953391; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
     
  0.900
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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