Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dctSPAS/PAC sensor signal transduction histidine kinase; IMG reference gene:2512955941; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (661 aa)    
Predicted Functional Partners:
dctR
Two component transcriptional regulator, LuxR family; IMG reference gene:2512955940; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 0.999
dctP
TRAP-T family transporter, C4-dicarboxylate-binding protein DctP; IMG reference gene:2512955942; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family.
 
   
 0.955
RSP_0085
Multisensor hybrid histidine kinase; IMG reference gene:2512955075; PFAM: Response regulator receiver domain; His Kinase A (phospho-acceptor) domain; PAS fold; Hpt domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box; truncated by 19 aa.
  
 
 0.941
RSP_0512
PAS/PAC sensor hybrid histidine kinase; IMG reference gene:2512955524; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
0.935
RSP_1306
PAS sensor Signal Tranduction Histidine Kinase; IMG reference gene:2512956353; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
  
 
 0.935
RSP_1357
Cytoplasmic sensor hybrid histidine kinase; IMG reference gene:2512956404; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
  
 
 0.919
RSP_1567
Putative sensory transduction histidine kinase; IMG reference gene:2512953462; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
  
 
 0.919
gfdS
IMG reference gene:2512954842; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
  
 
 0.919
dorS
IMG reference gene:2512956545; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
 
 
0.908
nifA
NifA transcriptional activator; IMG reference gene:2512955560; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein.
   
 
 0.902
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.