node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_0750 | aroB | RSP_0750 | RSP_2818 | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.581 |
RSP_0750 | ispA | RSP_0750 | RSP_1135 | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.938 |
RSP_0750 | ubiA | RSP_0750 | RSP_1008 | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.978 |
RSP_0750 | ubiE | RSP_0750 | RSP_1338 | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.655 |
RSP_0750 | ubiG | RSP_0750 | RSP_1175 | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.422 |
RSP_0750 | ubiX | RSP_0750 | RSP_0468 | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.556 |
RSP_2953 | ubiA | RSP_2953 | RSP_1008 | Glutaredoxin-related protein; IMG reference gene:2512954918; PFAM: Glutaredoxin; TIGRFAM: monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.813 |
RSP_2953 | ubiG | RSP_2953 | RSP_1175 | Glutaredoxin-related protein; IMG reference gene:2512954918; PFAM: Glutaredoxin; TIGRFAM: monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.415 |
aroB | RSP_0750 | RSP_2818 | RSP_0750 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.581 |
aroB | ispA | RSP_2818 | RSP_1135 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.715 |
aroB | ubiA | RSP_2818 | RSP_1008 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.783 |
aroB | ubiD | RSP_2818 | RSP_0467 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 3-octaprenyl-4hydroxybenzoate decarboxylase; IMG reference gene:2512955478; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | 0.614 |
aroB | ubiE | RSP_2818 | RSP_1338 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.724 |
aroB | ubiX | RSP_2818 | RSP_0468 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Putative 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.779 |
bchP | ispA | RSP_0277 | RSP_1135 | Geranylgeranyl hydrogenase; IMG reference gene:2512955284; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family. | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.658 |
bchP | ubiA | RSP_0277 | RSP_1008 | Geranylgeranyl hydrogenase; IMG reference gene:2512955284; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.852 |
ispA | RSP_0750 | RSP_1135 | RSP_0750 | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.938 |
ispA | aroB | RSP_1135 | RSP_2818 | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.715 |
ispA | bchP | RSP_1135 | RSP_0277 | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl hydrogenase; IMG reference gene:2512955284; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family. | 0.658 |
ispA | ubiA | RSP_1135 | RSP_1008 | Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.763 |