STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoE1RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor until released. Sigma-E controls a transcriptional response to singlet oxygen, a by-product of photosynthesis; its continuous activity requires constant exposure to singlet oxygen. The regulon has about 180 genes that protect against or repair damage induced by singlet oxygen, including itself and rpoH2, a heat shock- [...] (181 aa)    
Predicted Functional Partners:
chrR
anti-ECFsigma factor, ChrR; Anti-sigma factor that inhibits the activity of the extracytoplasmic function (ECF) sigma-E factor (RpoE), thereby indirectly regulating the transcription of the cycA and rpoE genes. ECF sigma factors are held in an inactive form by a cognate anti-sigma factor.
 
 
 0.999
RSP_1091
Putative cyclopropane/cyclopropene fatty acid synthesis protein, flavin amine oxidase; IMG reference gene:2512956136; PFAM: Flavin containing amine oxidoreductase.
 
  
 0.972
RSP_1090
Hypothetical protein; IMG reference gene:2512956135; PFAM: Protein of unknown function (DUF1365).
 
  
 0.955
rpoH1
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
  
 0.863
RSP_1087
Short-chain dehydrogenase/reductase family member; IMG reference gene:2512956132; PFAM: short chain dehydrogenase.
 
   
 0.857
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
  
 0.850
RSP_1088
Hypothetical protein; IMG reference gene:2512956133.
 
  
 0.849
rpoH2
RNA polymerase, sigma 32 subunit, RpoH; IMG reference gene:2512955616; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; alternative sigma factor RpoH.
  
  
 0.847
RSP_1089
Sugar/cation symporter, GPH family; IMG reference gene:2512956134.
 
  
 0.828
RSP_1409
Beta-Ig-H3/Fasciclin; IMG reference gene:2512956456; PFAM: Fasciclin domain.
 
  
 0.798
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.