node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GutQ | envA | RSP_1153 | RSP_2115 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.868 |
GutQ | kdsB | RSP_1153 | RSP_1160 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | IMG reference gene:2512956204; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | 0.908 |
GutQ | kdtA | RSP_1153 | RSP_1461 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.825 |
GutQ | kdtA1 | RSP_1153 | RSP_2394 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | Putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.867 |
GutQ | lpxA | RSP_1153 | RSP_2714 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.891 |
GutQ | lpxB | RSP_1153 | RSP_2716 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.861 |
GutQ | lpxD | RSP_1153 | RSP_2775 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; IMG reference gene:2512954725; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 0.899 |
GutQ | lpxK | RSP_1153 | RSP_1462 | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.884 |
RSP_3326 | kdsB | RSP_3326 | RSP_1160 | IMG reference gene:2512956834; PFAM: Low molecular weight phosphotyrosine protein phosphatase. | IMG reference gene:2512956204; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | 0.788 |
envA | GutQ | RSP_2115 | RSP_1153 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.868 |
envA | kdsB | RSP_2115 | RSP_1160 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | IMG reference gene:2512956204; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | 0.842 |
envA | kdtA | RSP_2115 | RSP_1461 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.943 |
envA | kdtA1 | RSP_2115 | RSP_2394 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Putative 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.844 |
envA | lpxA | RSP_2115 | RSP_2714 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.997 |
envA | lpxB | RSP_2115 | RSP_2716 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.976 |
envA | lpxD | RSP_2115 | RSP_2775 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; IMG reference gene:2512954725; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. | 0.997 |
envA | lpxK | RSP_2115 | RSP_1462 | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.975 |
kdsB | GutQ | RSP_1160 | RSP_1153 | IMG reference gene:2512956204; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | Sugar phosphate Isomerase; IMG reference gene:2512956197; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; extended by 14 aa; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.908 |
kdsB | RSP_3326 | RSP_1160 | RSP_3326 | IMG reference gene:2512956204; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | IMG reference gene:2512956834; PFAM: Low molecular weight phosphotyrosine protein phosphatase. | 0.788 |
kdsB | envA | RSP_1160 | RSP_2115 | IMG reference gene:2512956204; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.842 |