STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fxsAIMG reference gene:2512956282; PFAM: FxsA cytoplasmic membrane protein. (158 aa)    
Predicted Functional Partners:
hslV
HslV component of HslUV peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
    0.847
RSP_1489
Thioredoxin; IMG reference gene:2512953381; PFAM: Thioredoxin; TIGRFAM: thioredoxin.
   
    0.846
RSP_3836
Putative metal-dependent hydrolase; IMG reference gene:2512956499; PFAM: Amidohydrolase family.
  
    0.808
secB
Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
    0.735
RSP_1241
Putative Smr protein/MutS2; IMG reference gene:2512956285; PFAM: Smr domain.
 
     0.722
RSP_1239
Hypothetical protein; IMG reference gene:2512956283; PFAM: Tim44-like domain.
  
    0.700
RSP_1240
Putative membrane-bound lytic murein transglycosylase A transmembrane protein; IMG reference gene:2512956284; PFAM: MltA specific insert domain; 3D domain.
       0.681
RSP_1572
Heat shock protein, Hsp20 family; IMG reference gene:2512953468; PFAM: Hsp20/alpha crystallin family; truncated by 9 aa; Belongs to the small heat shock protein (HSP20) family.
  
    0.555
htpx
Heat shock protein; IMG reference gene:2512955568; PFAM: Peptidase family M48; Belongs to the peptidase M48B family.
   
  
 0.549
hslU
ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
   
    0.502
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.