STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_1502GAF domain protein; IMG reference gene:2512953394; PFAM: GAF domain. (150 aa)    
Predicted Functional Partners:
TyrB
Aromatic amino acid aminotransferase apoenzyme; IMG reference gene:2512955918; PFAM: Aminotransferase class I and II.
    
  0.912
RSP_2124
Methionine synthase I; IMG reference gene:2512954048; PFAM: Homocysteine S-methyltransferase.
     
  0.900
RSP_2768
Pterin binding enzyme; IMG reference gene:2512954718; PFAM: Pterin binding enzyme.
     
  0.900
RSP_3346
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.900
RSP_3347
Methionine synthase (B12-dependent); IMG reference gene:2512956856; PFAM: Homocysteine S-methyltransferase.
     
  0.900
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.900
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
    
 0.763
RSP_1503
Hypothetical protein; IMG reference gene:2512953395; PFAM: Glutathione-dependent formaldehyde-activating enzyme; extended by 8 aa.
       0.729
RSP_1501
Antisigma-factor antagonist (STAS) domain protein; IMG reference gene:2512953393; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
       0.671
RSP_3399
IMG reference gene:2512956909; PFAM: Carbon-nitrogen hydrolase.
 
 
    0.654
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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