STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_1505Putative Metallo-phosphoesterase; IMG reference gene:2512953398; TIGRFAM: phosphoesterase, MJ0936 family. (251 aa)    
Predicted Functional Partners:
ham1
dITPase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.862
RSP_2937
Putative phosphonate metabolism protein; IMG reference gene:2512954901; PFAM: Protein of unknown function (DUF1045); TIGRFAM: putative phosphonate metabolism protein.
  
  
 0.862
RSP_1507
Aldehyde dehydrogenase; IMG reference gene:2512953399; PFAM: Aldehyde dehydrogenase family.
  
    0.779
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.592
ucpA1
Short-chain dehydrogenase; IMG reference gene:2512955172; PFAM: short chain dehydrogenase.
   
   0.484
RSP_2679
IMG reference gene:2512954624; PFAM: Eukaryotic and archaeal DNA primase small subunit; ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain; DNA ligase D; DNA polymerase LigD, polymerase domain; DNA ligase D, 3'-phosphoesterase domain.
    
 
 0.434
RSP_1205
IMG reference gene:2512956249; PFAM: Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.426
RSP_0337
Putative phospodiesterase; IMG reference gene:2512955346; PFAM: Calcineurin-like phosphoesterase.
  
   
 0.420
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.