STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (463 aa)    
Predicted Functional Partners:
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.974
RSP_2917
Putative cystathionine gamma-synthase beta-lyase; IMG reference gene:2512954879; PFAM: Cys/Met metabolism PLP-dependent enzyme.
  
 0.972
RSP_2431
O-acetylhomoserine sulfhydrylase; IMG reference gene:2512954375; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
   
 
 0.970
RSP_3346
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.967
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.951
RSP_2124
Methionine synthase I; IMG reference gene:2512954048; PFAM: Homocysteine S-methyltransferase.
  
 
 0.936
RSP_3347
Methionine synthase (B12-dependent); IMG reference gene:2512956856; PFAM: Homocysteine S-methyltransferase.
  
 
 0.934
RSP_2768
Pterin binding enzyme; IMG reference gene:2512954718; PFAM: Pterin binding enzyme.
  
 
 0.932
cysK
O-acetylserine (Thiol)-lyase, cysteine synthase; IMG reference gene:2512954071; PFAM: Pyridoxal-phosphate dependent enzyme.
  
 0.931
RSP_3758
IMG reference gene:2512957291; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm).
     
 0.903
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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