STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prrCPrrC; IMG reference gene:2512953414; PFAM: SCO1/SenC. (231 aa)    
Predicted Functional Partners:
cox11
Cytochrome C oxidase assembly protein; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.
 
 
 0.984
prrA
PrrA (RegA), Response regulator involved in oxygen regulation of photosynthesis genes; Member of the two-component regulatory system RegB/RegA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in response to a decrease in oxygen tension.
  
  
 0.950
coxII
Cytochrome c oxidase polypeptide II precursor (Cytochrome AA3 subunit 2); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 0.940
cox15
Putative cytochrome oxidase assembly factor; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.
 
 
 0.915
RSP_0725
Thioredoxin, thioldisulfide interchange protein; IMG reference gene:2512955748; PFAM: AhpC/TSA family.
 
 
 0.900
RSP_0118
IMG reference gene:2512955109; PFAM: Cytochrome C oxidase subunit II, periplasmic domain; Cytochrome c.
  
 
 0.889
surf-1
Surf1 protein; IMG reference gene:2512953739; PFAM: SURF1 family.
 
  
 0.887
prrB
Sensor histidine kinase PrrB (RegB); Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as well as in regulation of expression of genes involved in alternative CO2 fixation pathways. Phosphorylates RegA/PrrA.
  
  
 0.864
pccA
Biotin carboxyl carrier protein;biotin carboxylase; IMG reference gene:2512954118; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; truncated by 29 aa.
   
  
 0.854
qoxB
QoxB, Quinol oxidase subunit II; IMG reference gene:2512956600; PFAM: Cytochrome C oxidase subunit II, periplasmic domain; non-canonical start codon; truncated by 90 aa.
  
 
 0.849
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.