node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_0784 | mviN | RSP_0784 | RSP_1810 | IMG reference gene:2512955811; PFAM: Acetyltransferase (GNAT) family. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.623 |
RSP_1812 | RSP_1814 | RSP_1812 | RSP_1814 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512953719; PFAM: LppC putative lipoprotein. | Holliday junction resolvase-like putative endonuclease; IMG reference gene:2512953721; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. | 0.697 |
RSP_1812 | glnD | RSP_1812 | RSP_1811 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512953719; PFAM: LppC putative lipoprotein. | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.843 |
RSP_1812 | mviN | RSP_1812 | RSP_1810 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512953719; PFAM: LppC putative lipoprotein. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.843 |
RSP_1812 | rsmI | RSP_1812 | RSP_1813 | Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512953719; PFAM: LppC putative lipoprotein. | Putative S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.780 |
RSP_1814 | RSP_1812 | RSP_1814 | RSP_1812 | Holliday junction resolvase-like putative endonuclease; IMG reference gene:2512953721; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. | Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512953719; PFAM: LppC putative lipoprotein. | 0.697 |
RSP_1814 | glnD | RSP_1814 | RSP_1811 | Holliday junction resolvase-like putative endonuclease; IMG reference gene:2512953721; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | 0.697 |
RSP_1814 | mviN | RSP_1814 | RSP_1810 | Holliday junction resolvase-like putative endonuclease; IMG reference gene:2512953721; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.699 |
RSP_1814 | rsmI | RSP_1814 | RSP_1813 | Holliday junction resolvase-like putative endonuclease; IMG reference gene:2512953721; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. | Putative S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.843 |
ftsI | mraY | RSP_2098 | RSP_2101 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.944 |
ftsI | mviN | RSP_2098 | RSP_1810 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.662 |
ftsI | rodA | RSP_2098 | RSP_2325 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.966 |
ftsI | rpoD | RSP_2098 | RSP_0395 | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.604 |
glnD | RSP_1812 | RSP_1811 | RSP_1812 | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | Amino acid/amide ABC transporter substrate-binding protein, HAAT family; IMG reference gene:2512953719; PFAM: LppC putative lipoprotein. | 0.843 |
glnD | RSP_1814 | RSP_1811 | RSP_1814 | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | Holliday junction resolvase-like putative endonuclease; IMG reference gene:2512953721; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. | 0.697 |
glnD | mviN | RSP_1811 | RSP_1810 | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.900 |
glnD | rsmI | RSP_1811 | RSP_1813 | UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism. | Putative S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.697 |
mraY | ftsI | RSP_2101 | RSP_2098 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | IMG reference gene:2512954022; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. | 0.944 |
mraY | mviN | RSP_2101 | RSP_1810 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Putative virulence factor, MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.613 |
mraY | rodA | RSP_2101 | RSP_2325 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.852 |