STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_1861IMG reference gene:2512953770; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain. (300 aa)    
Predicted Functional Partners:
RSP_1862
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.998
FolK
IMG reference gene:2512953572; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.
 
 
 0.995
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
       0.746
folE2
GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate.
 
   
 0.724
folC
Folylpolyglutamate synthetase; IMG reference gene:2512955963; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
  
  
 0.673
RSP_0393
Putative riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.626
RSP_6045
Hypothetical protein; IMG reference gene:2512954271.
  
     0.621
RSP_1860
Cell wall hydrolyses involved in spore germination; IMG reference gene:2512953769; PFAM: Cell Wall Hydrolase.
  
    0.606
fliH1
Putative flagellar biosynthesis/type III secretory pathway protein; IMG reference gene:2512956357.
  
     0.604
RSP_0549
Sporulation and cell division-related protein; IMG reference gene:2512955562; PFAM: Sporulation related domain.
 
     0.599
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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