node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PurD | purC | RSP_1847 | RSP_2126 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.953 |
PurD | purE | RSP_1847 | RSP_1571 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
PurD | purF | RSP_1847 | RSP_2454 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
PurD | purH | RSP_1847 | RSP_1100 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | IMG reference gene:2512956145; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.983 |
PurD | purK | RSP_1847 | RSP_1570 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.970 |
PurD | purL | RSP_1847 | RSP_2951 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.968 |
PurD | purM | RSP_1847 | RSP_1969 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2512953883; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. | 0.998 |
PurD | purN | RSP_1847 | RSP_1970 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
PurD | purQ | RSP_1847 | RSP_2128 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.996 |
PurD | purS | RSP_1847 | RSP_2127 | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | Component of phosphoribosylformylglycinamidine (FGAM) synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] | 0.941 |
purC | PurD | RSP_2126 | RSP_1847 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylamine--glycine ligase; IMG reference gene:2512953756; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.953 |
purC | purE | RSP_2126 | RSP_1571 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.994 |
purC | purF | RSP_2126 | RSP_2454 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.969 |
purC | purH | RSP_2126 | RSP_1100 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | IMG reference gene:2512956145; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.961 |
purC | purK | RSP_2126 | RSP_1570 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.931 |
purC | purL | RSP_2126 | RSP_2951 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.938 |
purC | purM | RSP_2126 | RSP_1969 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2512953883; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase. | 0.966 |
purC | purN | RSP_2126 | RSP_1970 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.952 |
purC | purQ | RSP_2126 | RSP_2128 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.968 |
purC | purS | RSP_2126 | RSP_2127 | IMG reference gene:2512954050; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. | Component of phosphoribosylformylglycinamidine (FGAM) synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] | 0.977 |