STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argKIMG reference gene:2512953931; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase. (323 aa)    
Predicted Functional Partners:
MeaA
(R)-ethylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- ethylmalonyl-CoA to (2S)-methylsuccinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R.sphaeroides growth on acetate as sole carbon source. Is highly specific for its substrate, ethylmalonyl-CoA, and accepts methylmalonyl-CoA only at 0.2% relative activity.
  
 0.998
mcmA
methylmalonyl-CoA mutase; Radical enzyme that catalyzes the transformation of (2R)- methylmalonyl-CoA to succinyl-CoA. Is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R.sphaeroides growth on acetate as sole carbon source.
  
 0.998
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
  
 0.838
epi
methylmalonyl-CoA epimerase; Promiscuous isomerase that catalyzes epimerization of both ethylmalonyl-CoA and methylmalonyl-CoA. Has thus a dual role in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R.sphaeroides growth on acetate as sole carbon source.
 
  
 0.809
pccB
propionyl-CoA carboxylase carboxyltransferase subunit; IMG reference gene:2512954113; PFAM: Carboxyl transferase domain; Belongs to the AccD/PCCB family.
 
  
 0.683
RSP_2013
DEAD/DEAH box helicase; IMG reference gene:2512953929; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent helicase HrpB.
  
    0.630
RSP_2014
IMG reference gene:2512953930; PFAM: Protein of unknown function (DUF3108).
       0.627
rpmB
LSU ribosomal protein L28P; IMG reference gene:2512953932; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
       0.623
RSP_0377
L-glutamine synthetase; IMG reference gene:2512955387; PFAM: Glutamine synthetase, catalytic domain.
   
  
 0.622
RSP_1934
Putative sulfurylase large subunit; IMG reference gene:2512953848; PFAM: XdhC and CoxI family; frameshift eliminated; joint gene, RSP_1934, RSP_1935.
 
 
    0.561
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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