Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RSP_2129Sensor Histidine kinase; IMG reference gene:2512954053; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (587 aa)    
Predicted Functional Partners:
RSP_2130
Two component, sigma54 specific transcriptional regulator, fis family; IMG reference gene:2512954054; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
 
 0.965
RSP_1612
Sigma-54 dependent transcriptional regulator; IMG reference gene:2512953510; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
 0.953
RSP_1611
Sensor histidine kinase; IMG reference gene:2512953509; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
  
 
0.926
RSP_1011
Hypothetical protein; IMG reference gene:2512956048.
  
     0.765
RSP_1200
Uncharacterized protein with SCP/PR1 domains; IMG reference gene:2512956244; PFAM: Cysteine-rich secretory protein family; truncated by 5 aa.
  
   
 0.701
RSP_2327
Hypothetical protein; IMG reference gene:2512954261.
  
     0.678
RSP_2816
Hypothetical protein; IMG reference gene:2512954795.
  
 
   0.669
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
       0.668
ntrX
Nitrogen assimilation transcriptional regulator, NtrX; IMG reference gene:2512954765; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
 
 
 0.665
RSP_1809
Putative membrane protein; IMG reference gene:2512953716; PFAM: Rhomboid family; extended by 114 aa; old pseudo, frameshift corrected.
  
     0.655
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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