node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_0169 | RSP_0616 | RSP_0169 | RSP_0616 | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Transcriptional regulator, AraC family; IMG reference gene:2512955632; PFAM: AraC-like ligand binding domain. | 0.505 |
RSP_0169 | gltA | RSP_0169 | RSP_1994 | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.615 |
RSP_0169 | pccR | RSP_0169 | RSP_2186 | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.544 |
RSP_0402 | pccR | RSP_0402 | RSP_2186 | Transcriptional regulator, TetR family; IMG reference gene:2512955411; PFAM: Bacterial regulatory proteins, tetR family. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.448 |
RSP_0616 | RSP_0169 | RSP_0616 | RSP_0169 | Transcriptional regulator, AraC family; IMG reference gene:2512955632; PFAM: AraC-like ligand binding domain. | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.505 |
RSP_0616 | pccR | RSP_0616 | RSP_2186 | Transcriptional regulator, AraC family; IMG reference gene:2512955632; PFAM: AraC-like ligand binding domain. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.443 |
RSP_2187 | RSP_2188 | RSP_2187 | RSP_2188 | Multidrug efflux pump, Major Facilitator Superfamily (MFS); IMG reference gene:2512954111; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily. | Hypothetical protein; IMG reference gene:2512954112; PFAM: Protein of unknown function, DUF486. | 0.658 |
RSP_2187 | pccB | RSP_2187 | RSP_2189 | Multidrug efflux pump, Major Facilitator Superfamily (MFS); IMG reference gene:2512954111; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily. | propionyl-CoA carboxylase carboxyltransferase subunit; IMG reference gene:2512954113; PFAM: Carboxyl transferase domain; Belongs to the AccD/PCCB family. | 0.462 |
RSP_2187 | pccR | RSP_2187 | RSP_2186 | Multidrug efflux pump, Major Facilitator Superfamily (MFS); IMG reference gene:2512954111; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.661 |
RSP_2188 | RSP_2187 | RSP_2188 | RSP_2187 | Hypothetical protein; IMG reference gene:2512954112; PFAM: Protein of unknown function, DUF486. | Multidrug efflux pump, Major Facilitator Superfamily (MFS); IMG reference gene:2512954111; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily. | 0.658 |
RSP_2188 | pccB | RSP_2188 | RSP_2189 | Hypothetical protein; IMG reference gene:2512954112; PFAM: Protein of unknown function, DUF486. | propionyl-CoA carboxylase carboxyltransferase subunit; IMG reference gene:2512954113; PFAM: Carboxyl transferase domain; Belongs to the AccD/PCCB family. | 0.533 |
RSP_2188 | pccR | RSP_2188 | RSP_2186 | Hypothetical protein; IMG reference gene:2512954112; PFAM: Protein of unknown function, DUF486. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.522 |
RSP_2965 | pccR | RSP_2965 | RSP_2186 | Transcriptional regulator, LysR family; IMG reference gene:2512954928; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.427 |
RSP_3621 | pccR | RSP_3621 | RSP_2186 | IMG reference gene:2512957153; PFAM: 'Cold-shock' DNA-binding domain; truncated by 9 aa. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.577 |
glcB | gltA | RSP_1980 | RSP_1994 | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | 0.981 |
glcB | pccR | RSP_1980 | RSP_2186 | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.547 |
gltA | RSP_0169 | RSP_1994 | RSP_0169 | Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.615 |
gltA | glcB | RSP_1994 | RSP_1980 | Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.981 |
gltA | pccB | RSP_1994 | RSP_2189 | Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | propionyl-CoA carboxylase carboxyltransferase subunit; IMG reference gene:2512954113; PFAM: Carboxyl transferase domain; Belongs to the AccD/PCCB family. | 0.511 |
gltA | pccR | RSP_1994 | RSP_2186 | Citrate synthase; IMG reference gene:2512953910; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. | Transcriptional Regulator, MerR family; Transcriptional regulator that controls propionyl-CoA assimilation through the methylmalonyl-CoA pathway via regulation of pccB expression; Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. | 0.441 |