STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_23132-hydroxyacid dehydrogenase; IMG reference gene:2512954247; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (328 aa)    
Predicted Functional Partners:
RSP_3071
Putative hydroxypyruvate reductase/glycerate kinase; IMG reference gene:2512956571; PFAM: MOFRL family.
 
 0.952
RSP_3442
2-hydroxyacid dehydrogenase; IMG reference gene:2512956953; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain.
 
 
 
0.929
RSP_0245
Serine-pyruvate aminotransferase/aspartate aminotransferase; IMG reference gene:2512955251; PFAM: Aminotransferase class-V.
  
 
 0.922
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.920
mcl1
beta-methylmalyl-CoA/L-malyl-CoA lyase; Involved in the ethylmalonyl-CoA pathway for acetate assimilation. Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to yield beta-methylmalyl-CoA. It is also able to catalyze the cleavage of (S)-citramalyl-CoA to yield acetyl-CoA and pyruvate, although this reaction is not involved in the ethylmalonyl- CoA pathway.
 
 
 0.919
glcD
Putative glycolate oxidase subunit protein; IMG reference gene:2512956058; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
  
 0.915
RSP_1019
Putative glycolate oxidase subunit protein; IMG reference gene:2512956057; PFAM: FAD binding domain.
  
 0.914
RSP_1018
Glycolate oxidase iron-sulfur subunit; IMG reference gene:2512956056; PFAM: Cysteine-rich domain.
  
 
 0.910
RSP_3366
IMG reference gene:2512956875; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
  
 
 
0.909
eda
IMG reference gene:2512954588; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
  
 
  0.904
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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