STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabI1Enoyl-(acyl-carrier-protein) reductase (NADH); IMG reference gene:2512954280; PFAM: short chain dehydrogenase. (274 aa)    
Predicted Functional Partners:
fabB
IMG reference gene:2512956686; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.992
fabD
Acyl-carrier-protein S-malonyltransferase; IMG reference gene:2512954627; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.982
fabZ
3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.965
fabF
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.961
RSP_3468
3-oxoacyl-(acyl carrier protein) synthase; IMG reference gene:2512956979.
  
 
 0.950
fabA
3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
 
 0.947
RSP_3062
AMP-dependent synthetase and ligase; IMG reference gene:2512956564; PFAM: short chain dehydrogenase.
 
 
 0.925
fabG
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
0.922
fabG1
Short-chain dehydrogenase/reductase; IMG reference gene:2512954482; PFAM: short chain dehydrogenase.
  
 
 0.915
RSP_0610
Putative 3-oxoacyl-(acyl-carrier-protein) reductase; IMG reference gene:2512955626; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.914
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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