STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_2372IMG reference gene:2512954312; PFAM: Aldehyde dehydrogenase family. (472 aa)    
Predicted Functional Partners:
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.940
RSP_0029
IMG reference gene:2512955012; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases.
  
 
 0.935
RSP_2196
3-hydroxyacyl-CoA dehydrogenase; IMG reference gene:2512954124; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.928
RSP_2962
Methylmalonate-semialdehyde dehydrogenase (acylating); IMG reference gene:2512954929; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
  
  
 
0.923
ackA
Putative acetate kinase (acetokinase); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.919
RSP_0154
3-hydroxyisobutyrate dehydrogenase; IMG reference gene:2512955150; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.917
adh
IMG reference gene:2512953732; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
 
 0.917
adhI
Alcohol dehydrogenase class III; Oxidizes long-chain aliphatic alcohols, long-chain hydroxylated fatty acids and S-hydroxymethylglutathione (hmGSH) in increasing order of preference. Shows little or no activity with short- chain aliphatic alcohols; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.917
RSP_2846
Putative 3-hydroxyisobutyrate dehydrogenase; IMG reference gene:2512954758; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; truncated by 8 aa.
  
 
 0.915
RSP_3171
3-hydroxyisobutyrate dehydrogenase; IMG reference gene:2512956681; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase.
  
 
 0.915
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.