node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdd | deoA | RSP_1594 | RSP_1595 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.999 |
cdd | guaA | RSP_1594 | RSP_0005 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.473 |
cdd | surE | RSP_1594 | RSP_2545 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.929 |
cmk | guaA | RSP_3591 | RSP_0005 | Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.505 |
cmk | guaB | RSP_3591 | RSP_2868 | Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.510 |
cmk | pyrF | RSP_3591 | RSP_1404 | Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.699 |
cmk | pyrH | RSP_3591 | RSP_2705 | Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.488 |
cmk | surE | RSP_3591 | RSP_2545 | Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.937 |
deoA | cdd | RSP_1595 | RSP_1594 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.999 |
deoA | guaA | RSP_1595 | RSP_0005 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.501 |
deoA | surE | RSP_1595 | RSP_2545 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.930 |
guaA | cdd | RSP_0005 | RSP_1594 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.473 |
guaA | cmk | RSP_0005 | RSP_3591 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase. | 0.505 |
guaA | deoA | RSP_0005 | RSP_1595 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.501 |
guaA | guaB | RSP_0005 | RSP_2868 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purA | RSP_0005 | RSP_0366 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.957 |
guaA | purB | RSP_0005 | RSP_2221 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | IMG reference gene:2512954150; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.962 |
guaA | pyrF | RSP_0005 | RSP_1404 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.599 |
guaA | pyrH | RSP_0005 | RSP_2705 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.805 |
guaA | surE | RSP_0005 | RSP_2545 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.954 |