STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gfaGlutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (196 aa)    
Predicted Functional Partners:
adhI
Alcohol dehydrogenase class III; Oxidizes long-chain aliphatic alcohols, long-chain hydroxylated fatty acids and S-hydroxymethylglutathione (hmGSH) in increasing order of preference. Shows little or no activity with short- chain aliphatic alcohols; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 0.996
xoxF
Putative pqq dehydrogenase protein; IMG reference gene:2512954521; PFAM: Pyrrolo-quinoline quinone coenzyme N-terminus; Pyrrolo-quinoline quinone coenzyme C-terminus; PQQ enzyme repeat; TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family.
 
 
 0.989
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
 0.961
cycB
Cytochrome c553i; IMG reference gene:2512954522; TIGRFAM: c-type cytochrome, methanol metabolism-related.
 
  
 0.951
xoxJ
Amino acid ABC transporter substrate-binding protein, PAAT family; IMG reference gene:2512954523; PFAM: Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein.
 
  
 0.936
cycI
Isocytochrome c2; IMG reference gene:2512954520; PFAM: Cytochrome c.
  
  
 0.786
RSP_2588
Hypothetical protein; IMG reference gene:2512954531.
 
    0.709
RSP_2574
IMG reference gene:2512954517; PFAM: Protein of unknown function (DUF2380).
 
     0.585
RSP_2595
Hypothetical protein; IMG reference gene:2512954538.
 
     0.576
RSP_0398
Dehydrogenase; IMG reference gene:2512955407; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
    
 0.566
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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