node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_1806 | RSP_2693 | RSP_1806 | RSP_2693 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.929 |
RSP_1806 | dnaJ | RSP_1806 | RSP_1172 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.723 |
RSP_1806 | rnc | RSP_1806 | RSP_1675 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.863 |
RSP_1806 | rplM | RSP_1806 | RSP_0022 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.821 |
RSP_1806 | rpmG | RSP_1806 | RSP_1887 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | LSU ribosomal protein L33P; IMG reference gene:2512953795; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family. | 0.844 |
RSP_1806 | rpoC | RSP_1806 | RSP_1712 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.842 |
RSP_1806 | rpsI | RSP_1806 | RSP_0021 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | SSU ribosomal protein S9P; IMG reference gene:2512955003; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. | 0.837 |
RSP_1806 | rpsO | RSP_1806 | RSP_1111 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.847 |
RSP_1806 | sucD | RSP_1806 | RSP_0966 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.597 |
RSP_2693 | RSP_1806 | RSP_2693 | RSP_1806 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.929 |
RSP_2693 | dnaJ | RSP_2693 | RSP_1172 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | 0.889 |
RSP_2693 | rnc | RSP_2693 | RSP_1675 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.896 |
RSP_2693 | rplM | RSP_2693 | RSP_0022 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.894 |
RSP_2693 | rpmG | RSP_2693 | RSP_1887 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | LSU ribosomal protein L33P; IMG reference gene:2512953795; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family. | 0.883 |
RSP_2693 | rpoC | RSP_2693 | RSP_1712 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.885 |
RSP_2693 | rpsI | RSP_2693 | RSP_0021 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | SSU ribosomal protein S9P; IMG reference gene:2512955003; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family. | 0.892 |
RSP_2693 | rpsO | RSP_2693 | RSP_1111 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.895 |
RSP_2693 | sucD | RSP_2693 | RSP_0966 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.908 |
RSP_2693 | ybeY | RSP_2693 | RSP_3598 | Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Metalloprotein, YbeY/UPF0054 family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.892 |
dnaJ | RSP_1806 | RSP_1172 | RSP_1806 | Chaperone, DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and [...] | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.723 |