node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cobA | cobB | RSP_2820 | RSP_3185 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.713 |
cobA | cobE | RSP_2820 | RSP_2822 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Putative precorrin methylase; IMG reference gene:2512954787; PFAM: Cobalamin synthesis G C-terminus. | 0.980 |
cobA | cobF | RSP_2820 | RSP_2819 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.941 |
cobA | cobI | RSP_2820 | RSP_2826 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-2 C20-methyltransferase; IMG reference gene:2512954783; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.944 |
cobA | cobJ | RSP_2820 | RSP_2824 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-3 methyltransferase; IMG reference gene:2512954784; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase. | 0.972 |
cobA | cobK | RSP_2820 | RSP_2825 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | precorrin-6A reductase; IMG reference gene:2512954785; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase. | 0.917 |
cobA | cobL | RSP_2820 | RSP_2823 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Putative Precorrin-6y C5,15-methyltransferase; IMG reference gene:2512954786; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit. | 0.981 |
cobA | cobM | RSP_2820 | RSP_2821 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Precorrin-4 C11-methyltransferase; IMG reference gene:2512954788; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.933 |
cobB | cobA | RSP_3185 | RSP_2820 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.713 |
cobB | cobE | RSP_3185 | RSP_2822 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative precorrin methylase; IMG reference gene:2512954787; PFAM: Cobalamin synthesis G C-terminus. | 0.950 |
cobB | cobF | RSP_3185 | RSP_2819 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.931 |
cobB | cobH | RSP_3185 | RSP_6217 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | IMG reference gene:2512954782; PFAM: Precorrin-8X methylmutase. | 0.999 |
cobB | cobI | RSP_3185 | RSP_2826 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C20-methyltransferase; IMG reference gene:2512954783; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.977 |
cobB | cobJ | RSP_3185 | RSP_2824 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-3 methyltransferase; IMG reference gene:2512954784; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase. | 0.971 |
cobB | cobK | RSP_3185 | RSP_2825 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-6A reductase; IMG reference gene:2512954785; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase. | 0.956 |
cobB | cobL | RSP_3185 | RSP_2823 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Putative Precorrin-6y C5,15-methyltransferase; IMG reference gene:2512954786; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit. | 0.975 |
cobB | cobM | RSP_3185 | RSP_2821 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C11-methyltransferase; IMG reference gene:2512954788; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.978 |
cobB | cobN | RSP_3185 | RSP_2827 | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobaltochelatase CobN subunit; IMG reference gene:2512954781; PFAM: CobN/Magnesium Chelatase. | 0.991 |
cobE | cobA | RSP_2822 | RSP_2820 | Putative precorrin methylase; IMG reference gene:2512954787; PFAM: Cobalamin synthesis G C-terminus. | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.980 |
cobE | cobB | RSP_2822 | RSP_3185 | Putative precorrin methylase; IMG reference gene:2512954787; PFAM: Cobalamin synthesis G C-terminus. | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.950 |