STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_29213-deoxy-D-arabinoheptulosonate-7-phosphate synthase; IMG reference gene:2512954884; PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II. (456 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
 
 0.949
tktA
Transketolase; IMG reference gene:2512954921; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
   
 
 0.941
RSP_0662
Putative chorismate mutase; IMG reference gene:2512955681; PFAM: Chorismate mutase type II; TIGRFAM: chorismate mutase related enzymes.
  
 
 0.870
pheAa
Chorismate mutase; IMG reference gene:2512956089; PFAM: Chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, alpha proteobacterial type.
  
 
 0.867
fbaB
Fructose-bisphosphate aldolase; IMG reference gene:2512954430; PFAM: DeoC/LacD family aldolase.
   
 
  0.804
cfxA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
     
  0.800
tklB
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
  0.800
cfxB
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
     
  0.800
ccr
crotonyl-CoA carboxylase/reductase; Catalyzes the NADPH-dependent reductive carboxylation of crotonyl-CoA ((2E)-butenoyl-CoA) to (2S)-ethylmalonyl-CoA, in the presence of CO2. This is a key reaction in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R.sphaeroides growth on acetate as sole carbon source. Is also able to accept acryloyl-CoA as an alternative substrate, yielding (2S)- methylmalonyl-CoA. To a lesser extent, when CO2 is absent, the enzyme also catalyzes the reduction of crotonyl-CoA to butanoyl-CoA.
      
 0.710
RSP_1340
IMG reference gene:2512956387; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
   
  
 0.618
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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