STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_3431Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2512956942; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (450 aa)    
Predicted Functional Partners:
RSP_3430
Transcriptional regulator, winged helix family; IMG reference gene:2512956941; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 0.996
kdpE
Two component transcriptional regulator, winged helix family; IMG reference gene:2512956313; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 0.964
pdhAb
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.943
RSP_1306
PAS sensor Signal Tranduction Histidine Kinase; IMG reference gene:2512956353; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
   
 
 0.914
dorS
IMG reference gene:2512956545; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain.
 
 
0.875
shp
Mono-heme class I cytochrome c; High-spin cytochrome. Transiently bind oxygen during autoxidation, which occurs with a half-life of 3 min with a 4-fold excess of O(2). Also binds carbon monoxide, azide and cyanide.
     
 0.848
RSP_0512
PAS/PAC sensor hybrid histidine kinase; IMG reference gene:2512955524; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
  
 
 0.843
RSP_3088
Two component transcriptional regulator, winged helix family; IMG reference gene:2512956590; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.832
RSP_1294
IMG reference gene:2512956340; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
   
 0.768
RSP_0085
Multisensor hybrid histidine kinase; IMG reference gene:2512955075; PFAM: Response regulator receiver domain; His Kinase A (phospho-acceptor) domain; PAS fold; Hpt domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box; truncated by 19 aa.
 
 
 0.761
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.