STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_3474Type VI secretion ATPase, ClpV1 family; IMG reference gene:2512956984; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: type VI secretion ATPase, ClpV1 family; Belongs to the ClpA/ClpB family. (889 aa)    
Predicted Functional Partners:
RSP_3478
Type VI secretion protein, EvpB/VC_A0108 family; IMG reference gene:2512956988; PFAM: Protein of unknown function (DUF877); TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family.
 
 0.970
dnaK
Heat shock protein (Hsp70, DnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.963
RSP_3200
Molecular chaperone, DnaK; IMG reference gene:2512956711; PFAM: Hsp70 protein.
  
 
 0.939
RSP_3477
Type VI secretion protein, VC_A0107 family; IMG reference gene:2512956987; PFAM: Protein of unknown function (DUF770); TIGRFAM: type VI secretion protein, VC_A0107 family.
 
  
 0.928
RSP_3486
Putative outer membrane protein, OmpA family; IMG reference gene:2512956996; PFAM: OmpA family; Uncharacterized protein conserved in bacteria (DUF2077); TIGRFAM: type IV / VI secretion system protein, DotU family; type VI secretion system OmpA/MotB family protein.
 
  
 0.926
RSP_3476
Hypothetical protein; IMG reference gene:2512956986; PFAM: ImpA-related N-terminal; TIGRFAM: type VI secretion-associated protein, ImpA family.
 
  
 0.923
RSP_3479
Hemolysin-coregulated protein (uncharacterized); IMG reference gene:2512956989; PFAM: Protein of unknown function (DUF796); TIGRFAM: type VI secretion system effector, Hcp1 family.
 
  
 0.917
RSP_3489
Rhs element Vgr protein; IMG reference gene:2512956999; PFAM: Phage-related baseplate assembly protein; TIGRFAM: type VI secretion system Vgr family protein; Rhs element Vgr protein.
 
  
 0.911
RSP_3482
Type VI secretion protein, VC_A0111 family; IMG reference gene:2512956992; PFAM: Protein of unknown function (DUF1305); TIGRFAM: type VI secretion protein, VC_A0111 family.
 
  
 0.897
grpE
Putative chaperone protein GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...]
  
 
 0.894
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.