node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP033 | RP220 | gene:17555116 | gene:17555301 | Unknown. | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | 0.850 |
RP100 | RP220 | gene:17555183 | gene:17555301 | 50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | 0.766 |
RP100 | RP238 | gene:17555183 | gene:17555319 | 50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | ELONGATION FACTOR P (efp); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). | 0.988 |
RP100 | RP816 | gene:17555183 | gene:17555885 | 50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | DNAK SUPPRESSOR PROTEIN HOMOLOG (dksA); Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. | 0.789 |
RP100 | RP817 | gene:17555183 | gene:17555886 | 50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | PROBABLE INTEGRASE/RECOMBINASE RIPX (xerC); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). | 0.645 |
RP220 | RP033 | gene:17555301 | gene:17555116 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | Unknown. | 0.850 |
RP220 | RP100 | gene:17555301 | gene:17555183 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | 50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.766 |
RP220 | RP238 | gene:17555301 | gene:17555319 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | ELONGATION FACTOR P (efp); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). | 0.586 |
RP220 | RP304 | gene:17555301 | gene:17555385 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11 (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. | 0.635 |
RP220 | RP361 | gene:17555301 | gene:17555441 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | INTEGRASE/RECOMBINASE XERD (xerD); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.548 |
RP220 | RP400 | gene:17555301 | gene:17555480 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | PUTATIVE SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE PRECURSOR (slt). | 0.552 |
RP220 | RP721 | gene:17555301 | gene:17555793 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | QUEUINE TRNA-RIBOSYLTRANSFERASE (tgt); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to f [...] | 0.583 |
RP220 | RP743 | gene:17555301 | gene:17555813 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | SERINE HYDROXYMETHYLTRANSFERASE (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.830 |
RP220 | RP816 | gene:17555301 | gene:17555885 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | DNAK SUPPRESSOR PROTEIN HOMOLOG (dksA); Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. | 0.754 |
RP220 | RP817 | gene:17555301 | gene:17555886 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | PROBABLE INTEGRASE/RECOMBINASE RIPX (xerC); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity). | 0.700 |
RP238 | RP100 | gene:17555319 | gene:17555183 | ELONGATION FACTOR P (efp); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). | 50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. | 0.988 |
RP238 | RP220 | gene:17555319 | gene:17555301 | ELONGATION FACTOR P (efp); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | 0.586 |
RP304 | RP220 | gene:17555385 | gene:17555301 | CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11 (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (purC); Belongs to the SAICAR synthetase family. | 0.635 |
RP304 | RP361 | gene:17555385 | gene:17555441 | CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11 (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. | INTEGRASE/RECOMBINASE XERD (xerD); Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.592 |
RP304 | RP400 | gene:17555385 | gene:17555480 | CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11 (cox11); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family. | PUTATIVE SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE PRECURSOR (slt). | 0.588 |