STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP544Unknown. (235 aa)    
Predicted Functional Partners:
RP677
Unknown; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.895
RP522
CYTIDYLATE KINASE (cmk).
  
  
 0.813
RP543
Unknown.
       0.773
RP260
EXODEOXYRIBONUCLEASE III (xthA1).
  
    0.763
RP676
EXODEOXYRIBONUCLEASE III (xthA2).
  
    0.763
RP418
PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (pheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.750
RP258
Unknown; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
   
 
 0.610
RP857
PSEUDOURIDYLATE SYNTHASE I (truA); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.536
RP236
INVASION PROTEIN A (invA); Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity). Preferentially hydrolyzes diadenosine penta-phosphate with ATP as one of the reaction products. Also able to hydrolyze diadenosine hexa-phosphate and diguanosine penta-phosphate. Has little or no activity on diadenosine tetra- and tri-phosphate, on diguanosine tetra- and tri-phosphate, on GDP-mannose, ADP-ribose, NADH and NAD(+); Bel [...]
   
 
 0.535
RP847
POSSIBLE PROTOPORPHYRINOGEN OXIDASE (hemK); Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; In the C-terminal section; belongs to the class I-like SAM- binding methyltransferase superfamily. TrmB family.
  
  
 0.502
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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