STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP731Unknown; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (191 aa)    
Predicted Functional Partners:
RP577
HOLO-[ACYL-CARRIER PROTEIN] SYNTHASE (acpS); Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
    
 0.903
RP732
DNA POLYMERASE III, EPSILON CHAIN (dnaQ); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease (By similarity).
     
 0.882
RP776
DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.855
RP008
(3R)-HYDROXYMYRISTOYL-[ACYL CARRIER PROTEIN] DEHYDRATASE (fabZ); Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
     
 0.786
RP730
Unknown.
       0.774
RP505
KPSF PROTEIN (kpsF); Belongs to the SIS family. GutQ/KpsF subfamily.
  
  
 0.716
RP418
PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (pheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.715
RP365
PUTATIVE ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE (fabI); Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
     
 0.713
RP428
BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE (ilvE); Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.702
RP202
RIBONUCLEASE HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.657
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.