node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP118 | RP740 | gene:17555201 | gene:17555810 | GTP-BINDING PROTEIN ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | HEMOLYSIN C (tlyC). | 0.445 |
RP118 | RP741 | gene:17555201 | gene:17555811 | GTP-BINDING PROTEIN ERA (era); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.838 |
RP136 | RP184 | gene:17555219 | gene:17555266 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.958 |
RP136 | RP535 | gene:17555219 | gene:17555615 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | SUPEROXIDE DISMUTASE (sodB); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.917 |
RP136 | RP600 | gene:17555219 | gene:17555679 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | Unknown. | 0.825 |
RP136 | RP620 | gene:17555219 | gene:17555699 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | 0.830 |
RP136 | RP634 | gene:17555219 | gene:17555711 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 50S RIBOSOMAL PROTEIN L17 (rplQ). | 0.999 |
RP136 | RP650 | gene:17555219 | gene:17555727 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 30S RIBOSOMAL PROTEIN S17 (rpsQ); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.999 |
RP136 | RP741 | gene:17555219 | gene:17555811 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.834 |
RP136 | RP751 | gene:17555219 | gene:17555821 | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 50S RIBOSOMAL PROTEIN L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.999 |
RP184 | RP136 | gene:17555266 | gene:17555219 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.958 |
RP184 | RP535 | gene:17555266 | gene:17555615 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | SUPEROXIDE DISMUTASE (sodB); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.934 |
RP184 | RP600 | gene:17555266 | gene:17555679 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | Unknown. | 0.662 |
RP184 | RP620 | gene:17555266 | gene:17555699 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | 0.949 |
RP184 | RP634 | gene:17555266 | gene:17555711 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 50S RIBOSOMAL PROTEIN L17 (rplQ). | 0.991 |
RP184 | RP650 | gene:17555266 | gene:17555727 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 30S RIBOSOMAL PROTEIN S17 (rpsQ); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.843 |
RP184 | RP741 | gene:17555266 | gene:17555811 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.843 |
RP184 | RP751 | gene:17555266 | gene:17555821 | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 50S RIBOSOMAL PROTEIN L21 (rplU); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.838 |
RP535 | RP136 | gene:17555615 | gene:17555219 | SUPEROXIDE DISMUTASE (sodB); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 50S RIBOSOMAL PROTEIN L11 (rplK); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.917 |
RP535 | RP184 | gene:17555615 | gene:17555266 | SUPEROXIDE DISMUTASE (sodB); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | DNAJ PROTEIN (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.934 |