node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP065 | RP417 | gene:17555148 | gene:17555497 | ARGINYL-TRNA SYNTHETASE (argS). | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.651 |
RP065 | RP418 | gene:17555148 | gene:17555498 | ARGINYL-TRNA SYNTHETASE (argS). | PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (pheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.949 |
RP065 | RP421 | gene:17555148 | gene:17555501 | ARGINYL-TRNA SYNTHETASE (argS). | LEUCYL-TRNA SYNTHETASE (leuS); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.958 |
RP065 | RP468 | gene:17555148 | gene:17555548 | ARGINYL-TRNA SYNTHETASE (argS). | TRYPTOPHANYL-TRNA SYNTHETASE (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.631 |
RP065 | RP556 | gene:17555148 | gene:17555636 | ARGINYL-TRNA SYNTHETASE (argS). | TYROSYL-TRNA SYNTHETASE (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.819 |
RP065 | RP617 | gene:17555148 | gene:17555696 | ARGINYL-TRNA SYNTHETASE (argS). | PROBABLE ISOLEUCYL-TRNA SYNTHETASE (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.985 |
RP065 | RP687 | gene:17555148 | gene:17555764 | ARGINYL-TRNA SYNTHETASE (argS). | VALYL-TRNA SYNTHETASE (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. | 0.804 |
RP065 | RP743 | gene:17555148 | gene:17555813 | ARGINYL-TRNA SYNTHETASE (argS). | SERINE HYDROXYMETHYLTRANSFERASE (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.537 |
RP065 | RP776 | gene:17555148 | gene:17555846 | ARGINYL-TRNA SYNTHETASE (argS). | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.778 |
RP065 | RP783 | gene:17555148 | gene:17555852 | ARGINYL-TRNA SYNTHETASE (argS). | SERYL-TRNA SYNTHETASE (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.784 |
RP417 | RP065 | gene:17555497 | gene:17555148 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | ARGINYL-TRNA SYNTHETASE (argS). | 0.651 |
RP417 | RP418 | gene:17555497 | gene:17555498 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (pheT); Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.999 |
RP417 | RP421 | gene:17555497 | gene:17555501 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | LEUCYL-TRNA SYNTHETASE (leuS); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.822 |
RP417 | RP468 | gene:17555497 | gene:17555548 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | TRYPTOPHANYL-TRNA SYNTHETASE (trpS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.708 |
RP417 | RP556 | gene:17555497 | gene:17555636 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | TYROSYL-TRNA SYNTHETASE (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.815 |
RP417 | RP617 | gene:17555497 | gene:17555696 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | PROBABLE ISOLEUCYL-TRNA SYNTHETASE (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.635 |
RP417 | RP687 | gene:17555497 | gene:17555764 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | VALYL-TRNA SYNTHETASE (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. | 0.814 |
RP417 | RP743 | gene:17555497 | gene:17555813 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | SERINE HYDROXYMETHYLTRANSFERASE (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.655 |
RP417 | RP776 | gene:17555497 | gene:17555846 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.611 |
RP417 | RP783 | gene:17555497 | gene:17555852 | PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (pheS); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | SERYL-TRNA SYNTHETASE (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.689 |